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At the Zhou Laboratory, we conduct interdisciplinary research in vascular biology, immunology, and regenerative medicine, focusing on the lung vascular niche — a specialized microenvironment within the lungs comprising endothelial cells (ECs), perivascular cells, immune cells, and the extracellular matrix (ECM). Our aim is to elucidate the interplay between these cells within the lung vascular niche and their roles in lung injury, repair, and regeneration. Our long-term goal is to identify therapeutic targets and develop innovative strategies to effectively treat severe lung conditions such as Acute Respiratory Distress Syndrome (ARDS) and Idiopathic Pulmonary Fibrosis (IPF), which currently lack effective medications.

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