The Zhou Laboratory
Vascular Biology, Immunology, and Regenerative Medicine

News & Updates
* Exciting news! On January 16, 2025, the Zhou lab was awarded another R01 grant! This funding will support our exploration of the role of capillaries in lung epithelial repair and regeneration.
* Welcome our new lab member, Van Dung Nguyen! Dung recently completed his master's degree in cardiovascular pharmacology and is eager to pursue PhD studies in vascular biology and immunology.
* Welcome our new lab member, Mo Zhu! With a master's degree in analytical chemistry, Mo has joined the lab as a research assistant and will be supporting the lab's daily operations.
* The first R01 grant in the Zhou laboratory officially started on June 15, 2024! This funding will enable us to study Perivascular Macrophages, a newly identified tissue macrophage population located alongside blood vessels, and their role in lung vascular function and endothelial repair following acute lung injury. We hope this research will provide insights for innovative strategies to rejuvenate endothelial regeneration and repair blood vessels, thereby promoting recovery from ARDS.
* The Zhou lab published an invited review paper titled "Roles of Macrophages and Endothelial Cells and Their Crosstalk in Acute Lung Injury" in Biomedicines on March 13, 2024. This paper highlights the most recent advances in the field. Read more.
* Dr. Zhou published groundbreaking findings on how the vascular niche orchestrates inflammation resolution in Nature Immunology. Read more..
* Our study, "The angiocrine Rspondin3 instructs interstitial macrophage transition via metabolic–epigenetic reprogramming and resolves inflammatory injury," published in Nature Immunology, garnered considerable attention within the field. Dr. Thomas Marichal, a leading expert in macrophage biology and immunology, provided insightful commentary in the same journal with his article titled " Endothelial cells instruct macrophages on how to Rspond to lung injury," which further illuminated the implications of our findings. Link to commentary.